Neonatal Nurse Practitioner Practice Exam

Infants with which condition require vigilant monitoring for tumors?

1. Cystic Fibrosis

2. Beckwith-Wiedemann Syndrome

3. Neonatal Abstinence Syndrome

4. Down Syndrome

The correct answer is: Beckwith-Wiedemann Syndrome

Beckwith-Wiedemann Syndrome is associated with an increased risk of tumor development, particularly within the first few years of life. This genetic disorder is characterized by overgrowth, distinctive facial features, macroglossia (enlarged tongue), and abnormalities of various organs. One of the most significant concerns with this syndrome is the predisposition to embryonal tumors, which include Wilms tumor (a type of kidney cancer) and hepatoblastoma (liver cancer). Due to this association, infants diagnosed with Beckwith-Wiedemann Syndrome must undergo vigilant monitoring for these tumors. Regular ultrasounds of the abdomen and kidneys, along with appropriate screening protocols, are vital for early detection and management of any tumor development. In contrast, while Cystic Fibrosis, Neonatal Abstinence Syndrome, and Down Syndrome have their own set of complications, they do not inherently carry the same level of risk for tumors as seen in Beckwith-Wiedemann Syndrome. Therefore, the need for diligent monitoring specifically for tumors is primarily linked to the characteristics and risks presented by Beckwith-Wiedemann Syndrome.